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Cleaning Validation Glossary

Emulsion

A combination of two liquids that are stablized by an agent

Emulsions are defined in PDA Technical Report 79, Particulate Matter Control in Difficult to Inspect Parenterals, as "A dispersed colloidal system consisting of two immiscible liquid phases generally stabilized with one or more suitable agents…". An emulsifying cleaning agent may be used to stabilize, and subsequently remove, difficult to clean liquids that would otherwise adhere to the equipment surface. Examples of elmusifying agents commonly used are Alkaline Liquinox and acidic Citranox, these are mixed into water to form a cleaning solution prior to being used to clean.

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